07/12/2012

Onset of Type 1 diabetes prevented in mice

Swedish researchers from the Karolinska Institutet managed to prevent onset of Type 1 diabetes in mice genetically susceptible to the disease by injecting them with specifically prepared cells.

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The cells injected by the Scandinavian researchers prevented insulin-producing pancreatic beta cells from being destroyed before clinical diabetes occurs. According to the study published in the scientific journal Diabetes, the team used 'NOD mice', i.e. mice that are genetically susceptible to spontaneously develop Type 1 diabetes and visualized the extent of the beta cells' immune-mediated with a specific three-dimensional imaging technique developed at Umeå University, Sweden.


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